When it comes to clinical studies regarding treatments for mesothelioma, or any other type of illness, it is important to understand the different reasoning behind a study. Treatments that are in the middle stages of testing in a clinical trial are often described as Phase II studies.
Phase II studiestest the effectiveness of a treatment or utility of a diagnostic test, determine how well it works, and attempt to better understand tolerability and toxicity of the treatment (or diagnostic test) in a larger patient group than in Phase I studies. While it is rare, Phase II studies can be randomized.
A specific number of patients are enrolled in the study, and patient outcomes such as survival, cancer-free survival, tumor control, quality of life, and toxicity may be measured. These studies often include a scientific research component, in which tissue from surgery or biopsy, blood or other biologic specimens are analyzed in order to correlate biologic parameters with outcomes.
Promising Phase II data can often be the basis for further testing via more advanced – and randomized – Phase III studies. It is more difficult to justify Phase III testing if Phase II outcomes prove to be clearly better than other treatments.
If you or a loved one has been exposed to asbestos by using certain products or working for certain companies and have subsequently been diagnosed with mesothelioma, there may be legal options worth pursuing to obtain a mesothelioma settlement. Contact a mesothelioma attorney if you have any questions about the details of asbestos law and what is needed to pursue a settlement from the manufacturer of the asbestos product (not necessarily your company).